Bisphosphonate-Related Osteonecrosis of the Jaws not associated to invasive dental procedures a retrospective analysis of 567 cases in an Italian multicenter study

Bisphosphonate-Related Osteonecrosis of the Jaws (BRONJ) is an area of bone exposure in the maxillo-facial region that did not heal within 8 weeks after identification by health care provider, in a patient who was receiving or had been exposed to a bisphosphonate (BP) without history of radiation therapy to the head and neck.